About Vet's Best
Vet's Best was founded in 1989 by veterinarian Dr. Dawn Curie Thomas, who set out to build gentler, plant-based wellness products for pets. Her first product, Hot Spots, treated the itchy allergic skin reactions that fleas often trigger, and the brand built its natural flea and tick line around cottonseed and clove-oil chemistry rather than the citrus and tea tree formulas that dominate the shelf. The company still operates under the tagline Where Nature Meets Science, pairing plant-based ingredients with formulations it says are vet-reviewed for safety.
Vet's Best is now part of Compana Pet Brands, a St. Louis pet wellness group whose portfolio also includes Nutri-Vet and Natural Care. The line has grown from flea and tick sprays into dental care, grooming, supplements, and home protection for both dogs and cats, and the company states its formulations avoid phthalates, artificial dyes, DEA, sulfates, and parabens. Citing 2023 Nielsen data, Vet's Best describes itself as the top-selling natural flea and tick brand in the US, a claim backed by more than three decades of operating specifically in that plant-based category.
Brand website: vetsbest.com
What Vet's Best makes
Vet's Best's range runs wider than the products we review. The lines we know best from our own testing are marked with a star:
Natural Flea & Tick
Sprays, waterless foams, shampoos, and collars built on cottonseed and clove-oil actives — featured on House of Mittens
Cat-Specific Flea & Tick
Flea and tick sprays and foams formulated and dosed specifically for cats rather than adapted from a dog product — featured on House of Mittens
Dental Care
Enzymatic gels, dental chews, and water additives for at-home oral hygiene
Grooming
Shampoos and wipes formulated for sensitive skin
Supplements & Wellness
Joint, digestive, and skin-and-coat support chews
Home Protection
Carpet and yard treatments that extend flea control beyond the pet itself
Why we recognized Vet's Best
The House of Mittens Top Brand recognition isn't paid for and can't be applied for. We award it to the brands whose products consistently stand out in our vet-reviewed category guides. Vet's Best earned it on the strength of the products below, evaluated the same way every product on this site is: assessed against feline-health criteria, used with real cats, and judged on merit.
Vet's Best products we rated highly
Vet's Best Flea & Tick Mist for Cats, Cotton Spice, Plant-Based, 6.3 oz
Formulated specifically for cats rather than adapted from a dog product, this spray uses a cottonseed and clove-oil base that avoids the citrus and tea tree derivatives behind most natural-product reactions we see in cats, and it carries a rating held steady across nearly twenty-five thousand reviews. It is also labeled safe to use on bedding, carpets, rugs, and drapes, so one bottle covers the cat and the environment where most of a flea population actually lives.
Read the Best Natural Flea Treatments for Cats of 2026 guide →
Vet's Best Waterless Flea & Tick Bath for Cats, Plant-Based, 5 oz
A no-rinse foam worked into the coat by hand instead of sprayed, which solves the real problem behind most searches for a bath-free treatment: many cats will not tolerate a bath, and a spray bottle triggers its own panic in plenty of others. It shares the same cottonseed and clove-oil base as the Vet's Best spray, so a cat already comfortable with the brand is not introduced to an unfamiliar chemistry.
Read the Best Natural Flea Treatments for Cats of 2026 guide →What earned Vet's Best the recognition
- Formulates specifically for cats rather than repackaging a dog product, using a cottonseed and clove-oil base that sidesteps the citrus and tea tree ingredients most associated with natural-product reactions in cats
- Built the brand around plant-based flea and tick chemistry starting in 1989, giving the natural flea care line more than three decades of formulation history in this specific category
- Offers a no-rinse foam application alongside its spray, giving owners of cats who won't tolerate a bath or a spray bottle a workable third option
- States its formulations exclude phthalates, artificial dyes, DEA, sulfates, and parabens across the product line
- Holds a rating sustained across tens of thousands of reviews on its cat-specific spray, a review depth that is rare in the natural flea care category